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An Introduction to Mass Spectrometry in the Health Sciences is designed to explain the science behind the operation of a mass spectrometer, to suggest methods for the production of reliable data and to flag cases where the production of false data can occur.
In 'An Introduction to Mass Spectrometry in the Health Sciences' (ISBN 978-1906715199) No “recipes” are given for specific analyte methods; these are plentiful in the scientific literature. The intention has been to prepare the reader to examine critically the published methods and to be aware of the major pitfalls in designing and implementing an analytical procedure. The first five chapters describe the operation of a mass spectrometer system and its use for qualitative and quantitative analysis while the final chapters describe some successful examples of application and explain how the methods chosen were designed to improve sensitivity, specificity and speed of analyses. Possible future applications are also discussed. A list of acronyms and a short section on the meaning of common terms is included at the end of the volume. Links to references, web sites and other useful information are included.
Dr Tony Mallet is a Professor at the University of Greenwich (UK) in the Faculty of Engineering & Science. He received the BMSS medal for lifetime contribution to mass spectrometry .
His involvement included fundamentals in fragmentation processes, metabolomics, proteomics and ion mobility mass spectrometry. He has been at the cutting edge instrumentation including direct analysis in real-time ionisation and a waters synapt G2 ESI-qTOF incorporating ion mobility.
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