Mass Spectrometry in Cancer Research

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Mass Spectrometry in Cancer Research provides an overview on how mass Spectrometers work and what type of information they provide. 

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    1300 g
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Mass Spectrometry in Cancer Research provides a broad examination of current strategies and techniques and their application to the study of:

(i) occupational and environmental carcinogens;

(ii) antineoplastic and chemopreventive agents;

(iii) pertinent proteins, lipids, nucleic acids and glycoconjugates. Also included are a chapter on instrumentation and methodologies for biologists and physicians and a brief review of the relevant concepts of cancer biology and medicine for mass spectrometrists.

It introduces appliations with succinct summaries of their biological, pharmacological, or medical background with references to recent reviews. It includes approximately 1800 references, many selected for informational or educational value and it includes approximately 240 figures and 30 tables.

This book is intended for: mass spectrometrists in research or those providing core services; researchers in biological, medical, pharmaceutical or environmental sciences; physicians in academic medicine; and academic/industrial research managers.

  • About the Author/Foreword/Mass Spectrometry: An Oncologist's Viewpoint/Preface/Acknowledgements
  • Terminology and Abbreviations
  • Chapter 1: Overview and Scope of Applications
  • Chapter 2: Instrumentation and Techniques of Mass Spectrometry
  • Chapter 3: Relevant Concepts of Cancer Medicine and Biology
  • Chapter 4: Metabolism and Biomarkers of Carcinogens
  • Chapter 5:Mechanism of Action and Metabolism of Antineoplastic and Chemopreventive Agents
  • Chapter 6: Strategies, Techniques, and Applications in Cancer Biochemistry and Biology
  • Index
  • Author
    John Roboz
  • Binding
  • Pages
  • Weight (g)
  • ISBN-10
  • ISBN-13

John Roboz is a Professor in the Department of Medicine (Division of Medical Oncology) of the Mount Sinai School of Medicine, New York. He has worked as a Senior Research Chemist for General Telephone and Electronics Research Laboratories (Bayside, NY) and then at the Central Research Laboratories of the Air Reduction Company (Murray Hill, NJ). In 1969, he joined the Mount Sinai School of Medicine as an Associate Professor in the Department of Pathology and in 1974 also joined the faculty of the Biomedical Sciences Doctoral Program. In 1980, he became Professor of Neoplastic Diseases in the Department of Neoplastic Diseases, which was later incorporated within the Department of Medicine.

His primary research interests have been in the development of mass spectrometric techniques in analytical pharmacology and biochemistry and the application of these methods in many collaborative studies with basic scientists developing new antineoplastic agents and clinicians conducing Phase 1 clinical trials.

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