Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation
J. Throck Watson & O. David Sparkman-4th Edition
Completely revised and updated, this text provides an easy–to–read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references.
This multi–disciplined text covers the fundamentals as well as recent advance in this topic, providing need–to–know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry
Edmond de Hoffmann and Vincent Stroobant-3rd Edition
The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra.
This new edition has been thoroughly revised and updated and has been redesigned to give the book a more contemporary look. As with previous editions it contains numerous examples, references and a series of exercises of increasing difficulty to encourage student understanding. Updates include: Increased coverage of MALDI and ESI, more detailed description of time of flight spectrometers, new material on isotope ratio mass spectrometry, and an expanded range of applications.
Mass Spectrometry, Third Edition is an invaluable resource for all undergraduate and postgraduate students using this technique in departments of chemistry, biochemistry, medicine,pharmacology, agriculture, material science and food science. It is also of interest for researchers looking for an overview of the latest techniques and developments.
Edited by Keith R. Jennings
The construction of Thompson’s mass spectrograph in Cambridge almost exactly a century ago followed by Aston’s improved instruments and his pioneering work on non-radioactive isotopes is widely known. In the sixty years or so since then, European scientists and engineers have made many major contributions to the development of new instruments and techniques. Accounts of these contributions in the scientific literature necessarily give little idea of the contributors themselves or of the difficulties that had to be overcome before success was achieved.
Most newcomers to mass spectrometry in the last ten years will have little concept of the difficulties faced in obtaining the mass spectra of four solid samples during a working day before the invention of the vacuum lock probe. This was followed by several hours of counting spectra and trying to interpret them. Many will never have seen a magnetic deflection instrument and will be familiar only with mass spectrometers having both the operation of the instrument and the interpretation of the data under computer control.
This book aims to give an insight into how some of the more important developments came about, from the advent of the first commercial instruments to the present day. The various accounts, several of which contain personal reminiscences, both provide a human background to these developments and convey the excitement of being part of the European mass spectrometry community during this period.